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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Zoledronic Acid and Calcium Supplement

Research Papers that Mention the Interaction

Zoledronic acid produced significant declines from baseline in serum and/or creatinine‐corrected urine C‐telopeptide (by 74%), N‐telopeptide (69%), pyridinium cross‐links (19–33%), and calcium (62%), with an increasing trend (by 12%) in bone alkaline phosphatase.
Journal of clinical pharmacology  •  2002  |  View Paper
After receiving a single dose of zoledronic acid , the patient developed hypocalcemia that persisted for approximately 60 days despite intravenous and oral calcium supplementation , likely because of excess unopposed osteoblastic activity.
Clinical genitourinary cancer  •  2007  |  View Paper