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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Zoledronic Acid
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ Zoledronic acid produced significant declines from baseline in serum and/or creatinine‐corrected urine C‐telopeptide (by 74%), N‐telopeptide (69%), pyridinium cross‐links (19–33%), and calcium (62%), with an increasing trend (by 12%) in bone alkaline phosphatase.”
Pharmacokinetics and Pharmacodynamics of Zoledronic Acid in Cancer Patients with Bone Metastases“After receiving a single dose of zoledronic acid , the patient developed hypocalcemia that persisted for approximately 60 days despite intravenous and oral calcium supplementation , likely because of excess unopposed osteoblastic activity.”
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