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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Zinc Cation
supplement:
Ferric Ion
Research Papers that Mention the Interaction
“The estimated maximal change in nNOS absorbance at approximately … caused by the L-arginine-dependent conversion of the ferric heme iron from hexacoordinate low-spin to pentacoordinate high-spin … by 50% in the presence of 50 microM Zn2+ , which reflects the increased initial amount …-spin ferric heme iron present.”
Inhibition of nitric oxide synthase activity by Zn2+ ion.“Common multivalent cations present in biological systems like Al3+, Cu2+, Fe3+ , Ca2+, and Mg2+, interfered with the measurement of Zn(II ) only when present in excess of 20, 33, 60, 500 and 30,000 times the Zn (II) concentration, respectively.”
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