Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Zinc Cation and Cobaltous Cation

supplement:

Zinc Cation

supplement:

Cobaltous Cation

Research Papers that Mention the Interaction

Cu2+ and Zn2+ , at 100 microM, inhibited the reaction almost completely, and the inhibitions by Co2+ and Ni2+ were also significant, while Mg2+ and Mn2+ did not appreciably affect the reaction.
Journal of biochemistry  •  1982  |  View Paper
The enzyme did not require any metal cofactors, although its activity was stimulated by 2 mM Co2+ and inhibited by Zn2+.
Applied Biochemistry and Biotechnology  •  2013  |  View Paper
Zn(II ) readily displaces Co(II ) from IAA as evinced by loss of the Co(II) spectral features.
Journal of inorganic biochemistry  •  2004  |  View Paper
Simultaneous treatment with Zn(II ) prevented largely the inhibition induced by Cd(II), Co(II ), and Ni(II), but only slightly in the case of Cu(II).
Carcinogenesis  •  2000  |  View Paper
The cations K+, Mg2+, Zn2+, Fe2+, Ni2+, Cu2+ Ca2+ and Cd2+ caused no increase in peptidase activity while Cd2+, Zn2+ and Cu2+ antagonized the effects of Co2+ and Mn2+.
Journal of general microbiology  •  1972  |  View Paper