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“Cu2+ and Zn2+ , at 100 microM, inhibited the reaction almost completely, and the inhibitions by Co2+ and Ni2+ were also significant, while Mg2+ and Mn2+ did not appreciably affect the reaction.”
Journal of inorganic biochemistry • 2004 | View Paper
“Simultaneous treatment with Zn(II ) prevented largely the inhibition induced by Cd(II), Co(II ), and Ni(II), but only slightly in the case of Cu(II).”
“The cations K+, Mg2+, Zn2+, Fe2+, Ni2+, Cu2+ Ca2+ and Cd2+ caused no increase in peptidase activity while Cd2+, Zn2+ and Cu2+ antagonized the effects of Co2+ and Mn2+.”