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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Zalcitabine and Levocarnitine

supplement:

Levocarnitine

Research Papers that Mention the Interaction

On … hand l-carnitine , in association with the mitochondrial cardiolipins, inhibits myopathy due … prescription of drugs [AZT (zidovudine), ddl (didanoside), or ddC (zalcitabine)], and the redox couple of α-lipoic-dihydrolipoic acid prevents production of the … oxygen species that trigger apoptosis of infected cells, with sphingomyelin breakdown to ceramides.
Lipids  •  2000  |  View Paper
The uptake of ddCTP and ddCDP-choline by mitochondria is inhibited by 3.0 mM l-carnitine in the cell-free system investigated; when added to U937 cells grown in the presence of 0.25 microM ddCyd, 3.0 mM l-carnitine partially abrogated the mitochondrial toxicity of ddCyd.
The Biochemical journal  •  1999  |  View Paper