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Last Updated: 3 years ago

Possible Interaction: Xylazine and Yohimbine

supplement:

Yohimbine

Research Papers that Mention the Interaction

Yohimbine was administered 46–110 min after the injection of xylazine , and the first sign of recovery occurred within 1–4 min.
Journal of Zoo and Wildlife Medicine  •  2021  |  View Paper
Xylazine (0.59 mg/kg) and ketamine (3.59 mg/kg) were used to capture animals and yohimbine (0.10 mg/kg) was used as an antagonist to xylazine to reduce recumbent time.
Australian veterinary journal  •  2016  |  View Paper
Yohimbine , rauwolscine and naloxone prevented action of xylazine 100 microg/paw.
European journal of pharmacology  •  2009  |  View Paper
Nasally administered flumazenil significantly reduced the duration of sedation with diazepam and midazolam while yohimbine (120 microg per nostril) effectively antagonized the effects of xylazine and detomidine.
Veterinary anaesthesia and analgesia  •  2006  |  View Paper
Intranasal administration of flumazenil, yohimbine , or atipamezole significantly decreased the duration of sedation induced by midazolam, xylazine , or detomidine, respectively.
Journal of the American Veterinary Medical Association  •  2006  |  View Paper
Yohimbine (1 mg/kg) produced greater antagonism of the pressor effects of guanabenz and xylazine than did prazosin.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
However, clonidine and xylazine depressed at lower concentrations the EJC and Δ[NA]CF responses to about the same extent; these effects were partially or completely reversed by yohimbine.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
At the conclusion of handling, the intravenous administration of yohimbine quickly abolished the sedative effect of xylazine , which allowed elk to be released without concern of physical injury due to ataxia.
Journal of wildlife diseases  •  2004  |  View Paper
Animals immobilized with Telazol®/xylazine had long recovery times with occasional resedation after antagonism with 6.5 mg of yohimbine.
Journal of wildlife diseases  •  2003  |  View Paper
Yohimbine , an alpha(2) adrenergic antagonist, abrogated the stimulatory action of both clonidine and xylazine , but not the suppressive proliferative activity of xylazine in vitro.
Journal of neuroimmunology  •  2001  |  View Paper
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