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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Warfarin
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“Vitamin … by warfarin … pyridoxal-5-phosphate (PAL-P) inhibited the activity, especially when microsomes were preincubated with PAL-P. The enzyme activity was not inhibited by N-methyltetrazolethiol (…, suggesting that the hypoprothrombinemia caused by beta-lactam antibiotics was not due to the inhibition of NADH-dependent vitamin K reductase.”
Effect of N-methyltetrazolethiol on liver microsomal vitamin K reductase.“Vitamins such as vitamin K, folic acid and pyridoxine are used to antagonise the effects of warfarin , methotrexate and INH respectively in the setting of toxicity or overdose.”
Antidotes in Poisoning
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