supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Warfarin
supplement:
Ginkgo Biloba Whole
Research Papers that Mention the Interaction
“ GBE extract increased C(max), AUC(0-144 min), AUC(0-infinity), t1/2, of warfarin significantly and decreased CL(F) of warfarin significantly (P < 0.05), and there were no singnificant difference of V(d) (F).”
[Effects of Ginkgo biloba extract on anticoagulation and blood drug level of warfarin in healthy wolunteers].“ Ginkgo biloba extract (GBE) increases the risk of bleeding if used in combination with warfarin , antiplatelet drugs, and certain other medications [4].”
“In contrast, GBE attenuated the anticoagulant action of warfarin.”
“These results suggest that GBE and ginkgolide B have no influence on blood coagulation in vivo, and that GBE attenuates the anticoagulation action of warfarin via induction of hepatic CYPs by bilobalide.”
Ginkgo biloba extract attenuates warfarin-mediated anticoagulation through induction of hepatic cytochrome P450 enzymes by bilobalide in mice.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback