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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Warfarin and Ginkgo Biloba Whole

Research Papers that Mention the Interaction

GBE extract increased C(max), AUC(0-144 min), AUC(0-infinity), t1/2, of warfarin significantly and decreased CL(F) of warfarin significantly (P < 0.05), and there were no singnificant difference of V(d) (F).
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica  •  2011  |  View Paper
Ginkgo biloba extract (GBE) increases the risk of bleeding if used in combination with warfarin , antiplatelet drugs, and certain other medications [4].
Anaesthesia  •  2005  |  View Paper
In contrast, GBE attenuated the anticoagulant action of warfarin.
These results suggest that GBE and ginkgolide B have no influence on blood coagulation in vivo, and that GBE attenuates the anticoagulation action of warfarin via induction of hepatic CYPs by bilobalide.
Phytomedicine : international journal of phytotherapy and phytopharmacology  •  2012  |  View Paper