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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin K
drug:
Teriparatide
Research Papers that Mention the Interaction
“Compared with monotherapy, vitamin K combined with teriparatide significantly increased serum Gla-OC level and the number of osteoblast, decreased serum CTX-I level, reduced the number of osteoclasts and increased bone density and strength.”
“This study showed that the efficacy of vitamin K combined with teriparatide is better than that of monotherapy.”
Combined treatment of vitamin K and teriparatide on bone metabolism and biomechanics in rats with osteoporosis“Taken together, these findings suggest that the treatment with VK and TPTD may have a therapeutic advantage over VK or TPTD monotherapy for postmenopausal osteoporosis, possibly by enhancing the bone formation through the actions on OC and osteoblasts.”
“The combination of VK and TPTD clearly increased the serum levels of Gla-OC (a specific marker for bone formation) and osteoblast surface (the number of osteoblasts attaching with the surface of cancellous bone), compared to VK or TPTD alone.”
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