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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“Patients should not take vitamin K antagonists concurrently with ibrutinib ; direct oral anticoagulants should be used if extended anticoagulation is strongly indicated.”
Ibrutinib‐associated bleeding: pathogenesis, management and risk reduction strategies“Atrial fibrillation in patients taking ibrutinib poses a unique challenge as the cumulative bleeding risk from the ibrutinib‐related antiplatelet effects added to the anticoagulation can be dangerously high, as confirmed by clinical trials which found unacceptable bleeding rates when ibrutinib was used in combination with vitamin K antagonists.”
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