supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Vitamin K
Research Papers that Mention the Interaction
“ Menadione did not alter trypan blue exclusion or51Cr release, but caused an increase in oxidized glutathione and shunt activity (P<0.001).”
Caco-2 cell metabolism of oxygen-derived radicals“The utility of the method was demonstrated by … with model compounds menadione and precocene I. Menadione , which contains a quinone moiety that undergoes redox cycling and induces concentration- and time-… in hepatocytes, resulted in decreased GSH concentrations with concomitant increase in concentrations of GSSG , as well as …-menadione conjugate.”
An ion exchange liquid chromatography/mass spectrometry method for the determination of reduced and oxidized glutathione and glutathione conjugates in hepatocytes.“Of the oxidizing agents, oxidized glutathione inhibited binding, whereas menadione and o-iodosobenzoate stimulated.”
“The ratio of reduced/oxidized glutathione accumulated in hyphal cells stressed with menadione decreased to only 0.4 in Δtrx2 from ∼1.0 observed in wild-type and other mutants.”
Subcellular localization of six thioredoxins and their antioxidant activity and contributions to biological control potential in Beauveria bassiana.“Our data showed that menadione induced cell-cycle arrest in the G1 phase, decreased intracellular GSH and GSSG concentrations, dose-dependently increased expression of ribonucleotide reductase and the activity of Yap1 pathway.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback