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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin K
drug:
Alendronate
Research Papers that Mention the Interaction
“Alendronate monotherapy does not decrease carboxylation of osteocalcin, and combination of vitamin K2 and alendronate brings further benefits on both osteocalcin carboxylation and BMD of femoral neck in postmenopausal women with osteoporosis.”
Response of serum carboxylated and undercarboxylated osteocalcin to alendronate monotherapy and combined therapy with vitamin K2 in postmenopausal women“… ALN … vitamin K2 increased not only total BMD (15%, P < 0.05) and trabecular BMD (32%, P < 0.05) but also maximum load (33%, P < 0.….05) and breaking force (33%, P < 0.05) of three-point bending test at the mid-diaphysis compared with the OVX-control group.”
Effects of combination treatment with alendronate and vitamin K2 on bone mineral density and strength in ovariectomized mice“In patients with PBC and established osteoporosis, the use of alendronate and vitamin K appears to cause an increase in bone mineral density.”
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