Possible Interaction: Vitamin E and Sodium Selenite

“Supplementation of the … 30 microM alpha-tocopherol or … sodium selenite led to a substantial increase of cellular alpha-tocopherol concentrations from 18 +/- 3.0 to 3179 +/- 93.0 pmol/10(… or cellular selenium concentrations from 0.17 +/- 0.02 to 1.75 +/- 0.16 ng/10(6) cells, respectively.”

“As a result, the co-administration of VE and/or SS against LPS-induced damage provides protection.”

“The co-treatment of VE and SS may be more effective than using them alone against LPS.”

“Following oral vitamin E (300 mg/kg) and sodium selenite (0.5 mg/kg) intake once a day for 4 weeks, XO activity decreased significantly.”

“ Sodium selenite , but not selenomethionine administration resulted in decreased liver vitamin E concentration.”

“The role of injectable combinations of vitamin E and sodium selenite in the occurrence of diaphragmatic hernias is worthy of additional investigation.”

“The use of combined vitamin E and sodium selenite prevered the toxic action of CCl4 on the liver in autumn, winter and spring and minimized it in summer.”

“L. infusion used separately lowered the toxic effect of tetracycline on the liver, while the use of vitamin E in combination with sodium selenite or Astragalus L. infusion prevented such an effect of the antibiotic.”

“The combined use of sodium selenite and vitamin E prevented the toxic effect of tetracycline on the liver in autumn, spring and summer.”

“The combination of sodium selenite with vitamin E recovered impaired bile excretion in autumn, spring and summer.”

“The use of antioxidants, such as tocopherol acetate in combination with sodium selenite promoted the recovery of liver excretion function in winter, spring and autumn.”