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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin E
drug:
Pregabalin
Research Papers that Mention the Interaction
“The concomitant administration of vitamin E significantly reduced all the previously mentioned biochemical and hormonal adverse effects caused by pregabalin.”
Molecular and hormonal changes caused by long-term use of high dose pregabalin on testicular tissue: the role of p38 MAPK, oxidative stress and apoptosis.“ Alpha tocopherol treatment significantly attenuated the deleterious effects induced by pregabalin.”
“Data suggests that thioctic acid or α‐tocopherol could positively impact the therapeutic profile of pregabalin , because they might be useful for reducing motor incoordination associated to pregabalin in patients with peripheral neuropathy.”
“Also combination of pregabalin with 100 mg/kg of vitamin E reversed Wallerian degeneration of sciatic nerve and the inflammatory responses to almost similar to sham group.”
“In addition, the %MPE following combination treatment of pregabalin (30 mg/kg) and vitamin E (100 mg/kg) was significantly higher than both vitamin E and control group.”
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