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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Vitamin E
drug:
Poloxamer 407
Research Papers that Mention the Interaction
“Interestingly, the combination of Pluronic F127 with vitamin E TPGS resulted in a synergistic effect in prolonging compound concentration upon dilution in SIF.”
Enhanced bioavailability of a poorly water-soluble weakly basic compound using a combination approach of solubilization agents and precipitation inhibitors: a case study.“Combinations of Pluronic F127 or Pluronic F108 with Vitamin E TPGS showed significantly stronger inhibition than the individual surfactants, indicating synergistic effects on inhibition of drug precipitation.”
Combination of Pluronic/Vitamin E TPGS as a potential inhibitor of drug precipitation.
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