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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Fat soluble vitamin levels remained within the normal range in the treatment group; the reduction seen in alpha-tocopherol levels in patients receiving orlistat was normalized by the decrease in plasma cholesterol concentrations.”
A one-year trial to assess the value of orlistat in the management of obesity.“ Orlistat significantly reduced the absorption of vitamin E (∼43% according to maximum concentration and ∼60% according to area under the concentration‐time curve), but not that of vitamin A, at the dose levels studied.”
“No effect was seen on vitamin A levels, but vitamin E levels became lower in the Orlistat group (P < 0.05, paired t test).(ABSTRACT TRUNCATED AT 250 WORDS)”
“ Orlistat causes a 30–60% reduction in absorption of the fat-soluble vitamins beta-carotene and vitamin E acetate and 2–12% of subjects treated with orlistat develop abnormally low levels of vitamins A, D, E, or beta-carotene.”
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