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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin E
supplement:
Naringenin
Research Papers that Mention the Interaction
“We report the synergic effect of α-TOC and NG in transglutaminase-induced differentiation of human PC-3 prostate cancer cells.”
Synergic effect of α-tocopherol and naringenin in transglutaminase-induced differentiation of human prostate cancer cells“Considering the established role of polyamines in cell differentiation, the synergism with NG makes α-TOC a potential drug for further study on the differentiation therapy in prostate cancer patients.”
“In addition, a significant reduction of both ornithine decarboxylase (ODC) expression and intracellular levels of polyamines, both well-known positive regulators of cell proliferation, accompanied the reduction of oxidative stress observed in the combined α-TOC and NG treatment.”
“ NG and α-TOC administered singularly or combined in the PC-3 cell line, affected the activity of several enzymes biomarkers of the cellular antioxidant activity, as well as the concentration of total glutathione (GSH + GSSG) and thiobarbituric acid reactive substances (TBARS).”
“In addition, naringenin significantly increased the activities of superoxide dismutase, catalase and GSH peroxidase as well as the level of GSH, vitamin C and vitamin E in liver of the oxytetracycline-treated rats.”
Influence of naringenin on oxytetracycline mediated oxidative damage in rat liver.
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