Possible Interaction: Vitamin E and Lignans

“The present study revealed for the first time, to our knowledge, that dietary sesame seed and sesame lignan increase not only vitamin E but also vitamin K concentrations in rat tissues.”

“We have shown that intake of sesame seed and its lignan increases vitamin E concentrations and decreases urinary excretion levels of vitamin E metabolites in male Wistar rats, suggesting inhibition of vitamin E catabolism by sesame lignan.”

“These results suggest that the sesame lignan SeOH increases tocopherol concentrations in animals by suppressing the conversion of gamma-tocopherol to gamma-CEHC.”

“We have previously reported that dietary sesame lignan elevates alpha-tocopherol concentration and decreases lipid peroxidation in tissues and serum of rats fed alpha-tocopherol.”

“Sesamin, a sesame lignan , on the other hand has been shown to increase vitamin E concentrations in rats.”

“We showed previously that dietary sesame seed and its lignans elevate the tocopherol concentration in rats.”

“Sesame lignans lowered the cholesterol concentration in serum, especially in combination with tocopherol , due to the inhibition of absorption from the intestine and suppression of synthesis in the liver.”