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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Vitamin E and Glutathione Disulfide

Research Papers that Mention the Interaction

Supplementation with lutein, zeaxanthin, or α-tocopherol increased GSH levels and GSH: GSSG ratio , particularly in response to oxidative stress.
Molecular vision  •  2011  |  View Paper
The results demonstrated that both DFO and vitamin E inhibit the iron accumulation and thus reverses the increase in oxidized glutathione (GSSG), oxidized to reduced glutathione ratios, .OH and lipid peroxidation levels.
Journal of Neural Transmission  •  2005  |  View Paper
In a second experiment, a similar treatment with 20 mg/kg VE attenuated RE-induced increase in the striatal ratio of oxidized/reduced glutathione (GSSG/GSH), an index of the oxidative stress process.
Progress in Neuro-Psychopharmacology and Biological Psychiatry  •  2003  |  View Paper
Unexpectedly, vitamin E increased concentrations of glutathione disulfide and thiobarbituric acid-reactive substance and decreased glutathione level in the muscle, compared with those of vehicle treatment, indicating that vitamin E enhanced unweighting-induced oxidative stress in skeletal muscle.
Journal of physiological anthropology and applied human science  •  2002  |  View Paper
Glutathione oxidation was competitively inhibited by vitamin E , Ki = 0.019 mmol/L. The retinal PHGPX is different from the PHGPX purified by others from heart and liver in molecular size.
Current eye research  •  1993  |  View Paper