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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Vitamin E
drug:
Gentamicin
Research Papers that Mention the Interaction
“Our results showed that vitamin E given concomitantly with gentamicin could protect the heart tissue against free radical injury.”
The effects of gentamicin on the activities of glutathione peroxidase and superoxide dismutase enzymes and malondialdehyde levels in heart tissues of guinea pigs.“Special attention was paid to the ability of α-tocopherol administered in combination with gentamicin to correct ultrastructural changes in the glomerular basal membrane and tubules.”
α-Tocopherol Reduces Morphological Changes and Oxidative Stress during Gentamicin-Induced Acute Renal Failure“Both hearing loss and vestibular dysfunction induced by gentamicin were significantly attenuated by alpha-tocopherol.”
“In conclusion, antioxidants such as alpha-tocopherol or tiopronin interfere with gentamicin and cisplatin damage and this suggests that they may be useful in preventing oto-vestibulotoxicity.”
“The present work indicates that, due to their antioxidant activity, vitamin E and probucol have potential protective effects against GM nephrotoxicity.”
“Both hearing loss and vestibular dysfunction induced by gentamicin were significantly attenuated by α-tocopherol.”
“In conclusion, antioxidants such as α-tocopherol or tiopronin interfere with gentamicin and cisplatin damage and this suggests that they may be useful in preventing oto-vestibulotoxicity.”
The role of antioxidants in protection from ototoxic drugs
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