Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Vitamin E and Folate

supplement:

Vitamin E

supplement:

Folate

Research Papers that Mention the Interaction

It has been suggested that folate deficiency may aggravate haemolysis in vitamin E deficiency,2' but though the patient's folate status was not certain his marrow was normoblastic, a finding which suggested that he did not have severe folate deficiency.
British medical journal  •  1975  |  View Paper
Additionally, it has been suggested that prevention of folate depletion by vitamin E consumption decreases homocysteine levels.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition  •  2019  |  View Paper
In women, the odds of meeting the folate and vitamin E EAR were lower in the Y/Y group.
International Journal of Obesity  •  2002  |  View Paper
The fortification of food with vitamin E and folate raised the low intakes from non-fortified food (about 50% of reference intake values) to about 80% (folate) and 100% (vitamin E) of the references.
European Journal of Clinical Nutrition  •  2000  |  View Paper
Although Vit E or folate had some protective effect, combination therapy with Vit E and folate attenuated all the changes due to H2O2 toxicity.
The present findings indicate that co-administration of Vit E and folate before and during pregnancy may maintain a viable pregnancy and contribute to its clinical efficacy for the treatment of some idiopathic infertility.
Toxicology mechanisms and methods  •  2018  |  View Paper
However, combined deprivation of folate and vitamin E resulted in levels of glutathione intermediate between those observed following deprivation of either agent, indicating that the lack of compensatory increase in glutathione following vitamin E deprivation was not due to overt neurotoxicity.
The differential response to vitamin E and folate deprivation is consistent with the possibility that specific differences in oxidative damage may result from deficiencies in either of these agents.
Journal of Alzheimer's disease : JAD  •  2003  |  View Paper