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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Vitamin E
supplement:
Ferric Ion
Research Papers that Mention the Interaction
“Pretreatment with 5 μmol/l vitamin E , a potent intracellular reactive oxygen species (ROS) scavenger could totally abolish ROS formation and cell viability reduction induced by ferric and ferrous iron treatment.”
Oxidative Stress Partially Contributes to Iron-Induced Alpha-Synuclein Aggregation in SK-N-SH Cells“Serum Zn+2, Cu+2, and Fe+3 levels were statistically significantly influenced by the administration of vitamin E (P < 0.05).”
Vitamin E modulates lung oxidative stress, serum copper, zinc, and iron levels in rats with pulmonary contusion.“When alpha-tocopherol was depleted by the interaction with ferric ion , it acted solely as a prooxidant, whereas if some alpha-tocopherol remained, it acted as an antioxidant.”
“ alpha-Tocopherol incorporated into artificial liposomal membranes reduced ferric ion rapidly to give more reactive ferrous ion, and alpha-tocopherol acted either as an antioxidant or as a prooxidant depending on the experimental conditions.”
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