Possible Interaction: Vitamin E and Epigallocatechin Gallate

“In the cells incubated with EGCG , the consumption of alpha-Toc and the formation of the oxidized form of GSH were suppressed.”

“When EGCG was included in the incubation with vitamin E or C, more antioxidant activities were consistently observed than when vitamins were added alone.”

“ EGCG exhibited a synergistic effect with α-tocopherol in scavenging 1,1-diphenyl-2-picylhydrazyl (DPPH) radical, thus displaying a direct free radical scavenging capacity.”

“ EGCG and EGC protected the depletion of α-tocopherol in the cells, and the glutathione content was enhanced by all four catechins.”

“ EGCG brought about an augmentation in the activities of enzymic antioxidants like superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glucose‐6‐phosphate dehydrogenase and improved the non‐enzymic antioxidants like tocopherol , ascorbic acid and glutathione.”

“Intake of green tea catechin (GTC) for 4 weeks was found to elevate vitamin E level in the mucosa of the rat large intestine.”

“The absorption of alphaTOH , used as a marker of extremely hydrophobic lipids, was significantly lower in EGCG (7.8+/-1.7 micromol) than in CAT (14.4+/-2.8 micromol) and CAT0 rats (16.8+/-2.1 micromol).”

“When vitamin E and EGCg or quercetin were combined, the individual effect was enhanced.”

“The addition of tea catechins to these diets significantly prevented the alpha-tocopherol concentration from decreasing.”

“These results suggest that tea catechins may counteract a decrease in alpha-tocopherol by acting as an antioxidant in vivo.”

“Conversely, butylated hydroxytoluene had no effect (EGCG loss, 78.1 ± 4.6%) and vitamin E enhanced the EGCG photolysis to 84.5 ± 3.4%.”