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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin E
Research Papers that Mention the Interaction
“ Vitamin E (tocopherol) enhances the growth inhibitory effects of adriamycin (ADR) on a variety of cancer cells in vitro.”
Vitamin E enhances the chemotherapeutic effects of adriamycin on human prostatic carcinoma cells in vitro.“Preincubation of PMNLs with vitamin E partially protected them from the effects of Adriamycin.”
“In six controls who ingested 1,600 units vitamin E daily for two weeks, platelet MDA formation induced by N‐ethyl maleimide, thrombin, and Adriamycin was decreased by 11‐20%.”
“Hence, eicosapentaenoic acid and vitamin E could be promising protective agents against doxorubicintoxicity.”
Eicosapentaenoic Acid and Vitamin E Against Doxorubicin Induced Cardiac and Renal Damages: Role of Cytochrome c and iNOS.“ConclusionsAntioxidant effect Vitamin E and telmisartan) have been shown to decrease doxorubicininduced cardiotoxicity.”
“ Doxorubicin treatment increased MDA, LDH, CK-MB levels significantly (P < 0.01), and were counteracted by administration of vitamin E and telmisartan, but did not significantly affect serum catalase activity.”
“This effect of doxorubicin was significantly suppressed by the antioxidants alpha-tocopherol , dexrazoxane, and epigallocatechin gallate.”
“Prednisone and vitamin E have protective effects against renal injuries induced by ADR in rats.”
“ DOX treatment induced an increase in thiobarbituric acid-reactive substances and vitamin E levels and a decrease in reduced glutathione content and aconitase activity.”
“Current results show that vitamin E in single oral dose failed to inhibit acute cardiotoxic activity of doxorubicin , but suspended further progression of the heart muscle damage over the time.”
“In sera of mice treated with vitamin E prior to doxorubicin , the creatine kinase and % alpha-HBDH activity were significantly reduced, compared to positive control.”
“In the present study we investigated whether vitamin E and catechin can reduce the toxic effects of doxorubicin.”
“We conclude that vitamin E and catechin significantly reduce doxorubicin-induced hepatotoxicity in rats.”
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