Possible Interaction: Vitamin E and Canthaxanthin

“ Canthaxanthin supplementation of the maternal diet at 12 mg/kg was associated with an increased α-tocopherol concentration in the liver of 1-d-old chicks and resulted in decreased tissue susceptibility to lipid peroxidation.”

“When α-Toc (300 μmol/L) was added to the oil emulsion’ the absorption of CTX was decreased by at least 50%.”

“We conclude that dietary administration of canthaxanthin modifies tocopherol status in murine tissues.”

“ Feeding canthaxanthin and retinyl palmitate but not beta-carotene, resulted in lower levels of plasma alpha-tocopherol.”

“These results extend to adult rats previous findings that excess retinyl palmitate alters vitamin E and carotenoid status prior to the manifestation of clinical signs of hypervitaminosis A. Additionally, canthaxanthin feeding lowers alpha-tocopherol and iron status in adult rats.”