Possible Interaction: Vitamin E and Calcium Supplement

“The bioaccessibility of vitamin E increased in the presence of calcium and phospholipids (DOPC) in LCT-emulsions, but decreased in MCT-emulsions.”

“Mast cells generate and release inflammatory compounds in asthma and allergic diseases and … a detrimental effect on the vessel wall, which can be inhibited by vitamin E. Vitamin E inhibits histamine release generated in activated mast cells, increases calcium Ca2 + uptake and prevents the oxidation of unsaturated fatty acids.”

“We also observed a correlation between calcium and vitamin E (r = +0.27; P = 0.02).”

“Finally, a pretreatment of cells with the antioxidant vitamin E blocked the CuLDL-induced increase in reactive oxygen species, in intracellular calcium rise and the CuLDL-induced NFAT-binding activity.”

“We find that vitamin E potently regulates the expression of ca.”

“When the combined effect of calcium and vitamin E was considered, the OR reached 0.4 (95% CI: 0.3-0.7) for subjects in the highest compared to those in the lowest intake tertile of both micronutrients.”

“Among micronutrients, beta-carotene, vitamin E and calcium showed the most consistent inverse associations.”

“Inclusion of myeloperoxidase inhibitors (cyanide, sodium azide and 3-amino-1,2,4-triazole), catalase, superoxide dismutase plus catalase, and alpha-tocopherol significantly protected (P less than 0.01) calcium uptake rates and Ca2+-ATPase activity of sarcoplasmic reticulum.”

“It is suggested that vitamin E acts to inhibit platelet internal contraction and secretion by preventing efflux of calcium from the dense tubular system.”

“ Vitamin E had no effect on uptake of calcium by the membrane vesicles, but showed a concentration dependent inhibition of the release of calcium induced by A23187.”

“… VitE significantly (p < 0.05) reduced aortic (from 38.4 ± 8.8 to 16.5 ± 1.4 mg/g), gastric (from 5.6 ± … to 1.2 ± 0.4 mg/g) and pulmonary (from 1.8 ± 0.3 to 0.3 ± 0.2 mg/g) calcium content in … HF diets.”