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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin E
drug:
Artemisinin
Research Papers that Mention the Interaction
“Iron probably catalyzes the generation of free radicals from artemisinin since alpha-tocopherol antagonizes the thiol-oxidizing activity of artemisinin and since a spin-trapped free radical signal can be seen by electron paramagnetic resonance only when artemisinin is incubated in the presence of iron.”
Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu)“In contrast, catalase, dithiothreitol and alpha-tocopherol reduced the effectiveness of qinghaosu in vitro.”
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