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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin E
supplement:
3-Nitrotyrosine
Research Papers that Mention the Interaction
“ δ-Tocopherol also effectively decreased oxidative DNA damage and nitrotyrosine formation and enhanced apoptosis in tumor cells; again, γ-tocopherol also was active in these regards but less so, and α-tocopherol was not.”
δ-Tocopherol Is More Active than α- or γ-Tocopherol in Inhibiting Lung Tumorigenesis In Vivo“There were significant correlations between alpha tocopherol and 3-NT (r = −0.285; P = 0.007) and MDA (r = −0.321; P = 0.002), whereas this relationship was not shown with PrCarb (r = −0.073; P = 0.496).”
“Immunohistochemical analysis showed that δ-T and γ-T treatments reduced the levels of 4-hydroxynonenal and nitrotyrosine and the expression of cyclin D1 in the colon, preserved the expression of PPAR-γ, and decreased the serum levels of prostaglandin E2 and 8-isoprostane.”
δ- and γ-Tocopherols, but not α-Tocopherol, Inhibit Colon Carcinogenesis in Azoxymethane-Treated F344 Rats“ Vitamin E reduced the oxidative damage, protein nitrotyrosilation , and tissue TNF-alpha levels.”
“Importantly, dietary supplementation with vitamin E abolished iNOS expression, lowered nitrotyrosines , p47-, p67-phox, and Rac1 levels, and suppressed HSP 70 and HO-1 proteins in c-Myc/TGF-alpha livers.”
“Dithiothreitol and vitamin E inhibited the increased formation of 3-nitrotyrosine.”
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