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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Cholecalciferol uptake was concentration-, temperature- and direction-dependent, and was significantly impaired by a co-incubation with cholesterol or tocopherol in Caco-2 cells.”
Vitamin D intestinal absorption is not a simple passive diffusion: evidences for involvement of cholesterol transporters.“Moreover, vitamin E was positively correlated with vitamin D (r=0.959, p < 0.001).”
“The observed association for vitamin D and vitamin E was significant among smokers but not among non-smokers.”
“ Vitamin D may be protective for muscle loss; a more alkalinogenic diet and diets higher in the anti-oxidant nutrients vitamin C and vitamin E may also prevent muscle loss.”
“… vitamin E … ( vitamin D3 ) an effect accompanied by a marked inhibition of the transcription factor, NF-kappa B. Curcumin, a potent inhibitor of tumor promotion and of … B activity, the effects of curcumin on the differentiation of HL-60 cells produced by low levels of vitamin D3 were measured.”
“In addition, supplementation with RRR-α-tocopherol in the feed negatively affected the plasma concentration of 25-hydroxycholecalciferol compared with supplementation with all-rac-α-tocopherol.”
“The water-soluble form of vitamin E have exerted a substantial antiswelling action exceeding the same of vitamin D , whereas vitamin C had no any effect.”
“ Vitamin E (0,726-7,26 IU) lowered the vitamin D toxicity, decreased contents of 25OHD3 in blood serum and activity of vitamin D3 25-hydroxylase enzymes in hepatocytes.”
“ Vitamin E (0.726-7.26 IU) significantly stimulated the effect of vitamin D3 (40 IU) in animals with D-hypovitaminosis and led to further increase of 25OHD3 content in the blood serum and activity of vitamin D3 25-hydroxylase enzymes in hepatocytes.”
“It was shown, that influence of vitamin E on mineral and D-vitamin metabolism depends on its doses and application period: physiological doses of vitamin E activate and large doses - inhibit the effect of vitamin D3 in regulation of mineral metabolism in the organism.”
[Influence of vitamin E application period on the mineral and D-vitamin metabolism in the organism].“Feeding 2,500 IU/kg of vitamin D3 overcame the effects of the high level of vitamin E , causing a significant (P < 0.05) interaction.”
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