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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin D
drug:
Temozolomide
Research Papers that Mention the Interaction
“Antitumor synergisms between temozolomide and Vitamin D and Vitamin D with Vitamin A derivatives were observed.”
From epidemiology and neurometabolism to treatment: Vitamin D in pathogenesis of glioblastoma Multiforme (GBM) and a proposal for Vitamin D + all-trans retinoic acid + Temozolomide combination in treatment of GBM“ TMZ and VD co-treatment also significantly inhibited tumor progression and prolonged survival duration in rat glioblastoma orthotopic xenograft models when compared with TMZ treatment alone.”
“These in vivo results are concordant with the aforementioned in vitro results, together revealing that the combined use of TMZ and VD exerts synergistic antitumor effects on rat models of glioblastoma and may represent an effective therapeutic strategy.”
Autophagy enhancement contributes to the synergistic effect of vitamin D in temozolomide-based glioblastoma chemotherapy
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