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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Vitamin D
drug:
Sitagliptin
Research Papers that Mention the Interaction
“Herein, we report the case of a patient with MM and selective IgG1 deficiency who showed remarkable clinical improvement after 2-year combination therapy with the DPP-4 inhibitor sitagliptin plus vitamin D3.”
Improvement of pure sensory mononeuritis multiplex and IgG1 deficiency with sitagliptin plus Vitamin D3.“Conclusion: These … demonstrate that sitagliptin in combination with VitD3 may accelerate the process of T2DM treatment by exerting synergic anti-inflammatory effects on immune system through upregulation of FOXP3 and IL-37, and downregulation of RORγt and BCL6 as well as IFN-γ, IL-17 and IL-21 production.”
“The determination of anti-GAD antibodies and C-peptide levels could be helpful in the follow-up of patients in use of sitagliptin and vitamin D3 , which could be associated with prolonged T1DM clinical remission.”
Four-year clinical remission of type 1 diabetes mellitus in two patients treated with sitagliptin and vitamin D3
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