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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“ Rapamycin and herceptin significantly reduced the level of cyclin D1 and D3 and increased the cleavage of caspase 3 suggesting an increased apoptosis.”
Rapamycin together with herceptin significantly increased anti‐tumor efficacy compared to either alone in ErbB2 over expressing breast cancer cells“We found that PK11195 plays a pro-autophagy role if associated with ATP and Vitamin D3 to be ineffective if co-incubated with Rapamycin and H2O2.”
“By using a panel of MM cell lines we showed that rapamycin induced G0/G1 arrest, an effect being associated with an increase of the cyclin-dependent kinase inhibitor p27 and a decrease of cyclins D2 and D3.”
“The induction of leukemia cell … response to the analogs of vitamin D was inhibited by LY294002 (phosphatidylinositol 3-kinase inhibitor), PD98059 (inhibitor …,2, an upstream regulator of extracellular-signal regulated kinase) and rapamycin (p70S6K inhibitor) pointing out that activation of signal … pathways unrelated to nVDR is necessary for differentiation.”
“ Rapamycin decreased the Ki in the IR-C (-32%) as well as in the CC (-26%) in the control rats.”
Rapamycin decreased blood-brain barrier permeability in control but not in diabetic rats in early cerebral ischemia
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