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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Vitamin D and Phenylbutyrate

supplement:

Vitamin D

Research Papers that Mention the Interaction

PBA co-treatment with 25(OH)D3 synergistically modulated expression of numerous vitamin D-response genes, including CAMP, CYP24A1, CXCL10 and IL-37.
This suggests that PBA augments vitamin D –mediated cathelicidin-dependent Mtb growth restriction by human macrophages and independently induces antimicrobial and anti-inflammatory action.
We also tested the ability of PBA to enhance the immunomodulatory actions of the vitamin D metabolite 25(OH)D3 during infection and synergistically inhibit intracellular Mtb growth.
PLoS pathogens  •  2015  |  View Paper