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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“Pharmacological treatment of patients with vitamin D3 may have the added therapeutic benefit of enhancing the intestinal absorption of folates.”
Vitamin D3 and Its Nuclear Receptor Increase the Expression and Activity of the Human Proton-Coupled Folate Transporter“ Vitamin D affects the absorption of folate in vitro, and perhaps of vitamin B12 (B12).”
“ Folate and vitamin D were significantly associated (p = 0.0001, r = 0.28).”
“We predict that the sub-optimal functioning of folate and vitamin D metabolic pathways, in concert, represents a potential novel risk pathway for adverse pregnancy outcomes.”
“Conversely, low nutritional calcium and folate enhance vitamin D catabolism.”
“Before folate treatment the homocysteine concentration was raised in all groups; following folate supplementation it was significantly decreased in the CC and CT groups, but not in the TT group.”
“Correspondingly, VitD3 markedly improved folate transport from maternal circulation into the embryos.”
“Interestingly, VitD3 not only inhibited placental inflammation but also attenuated LPS-induced downregulation of placental folate transporters.”
Supplementation with vitamin D3 during pregnancy protects against lipopolysaccharide-induced neural tube defects through improving placental folate transportation.
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