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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Vitamin D
drug:
Etidronate
Research Papers that Mention the Interaction
“3) EHDP , at a dose of 2.5 mg/kg/day, inhibited the vitamin D induced hypercalcemia. (”
The effect of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) on a rabbit model of athero-arteriosclerosis.“When disodium ethane-1-hydroxy-1,1-diphosphonate EHDP ) was administered (50 mg/kg b.wt) from 2 days before until 2 days after vitamin D3 treatment, cyst calcification was inhibited.”
Trichinella spiralis: Acceleration and inhibition of cyst calcification in rats“We conclude that the combined treatment with etidronate and alfacalcidol additively increases the mass of bone with normal quality, resulting in bone strengthening in ovx rats.”
“To examine whether either of the two known active vitamin D metabolites 1,25(OH)2D3 or 24,25(OH)2D3 could reverse the mineralization defect induced by 1‐hydroxyethylidene‐1,1‐bis phosphonate (EHDP), a model of EHDP‐induced rickets was used.”
“This dose of EHDP enhances the intestinal accumulation of a vitamin D3 metabolite with the chromatographic characteristics of 1,25-dihydroxycholecalciferol.”
“Abstract The administration of disodium-ethane-1-hydroxy-1,1-diphosphonate (20 mg/kg body weight subcutaneously) to chicks given adequate amounts of vitamin D 3 causes a hypercalcemia, inhibits bone mineralization, and inhibits intestinal calcium transport.”
“In rachitic chicks the disodium-ethane-1-hydroxy-1,1-diphosphonate treatment markedly reduces the 25-hydroxyvitamin D 3 -1-hydroxylase activity of kidney, but does not increase the 25-hydroxyvitamin D 3 -24-hydroxylase.”
“Medical cost of concurrent therapy alphacalcidol and etidronate ) for osteoporosis was compared with those of no treatment and single therapies (alphacalcidol or etidronate) .”
[Efficacy in medical cost of concurrent therapy for osteoporosis].
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