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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin D
drug:
Bryostatin 1
Research Papers that Mention the Interaction
“Combination 1,25(OH)(2)D(3) and bryostatin-1 treatment, resulted in decreased expression of the cyclin-dependent kinases Cdk2, Cdk1, and Cdk4, of cyclins E and D3 , and of the retinoblastoma binding protein (RBBP).”
1alpha,25-dihydroxyvitamin D3 and bryostatin-1 synergize to induce monocytic differentiation of NB4 acute promyelocytic leukemia cells by modulating cell cycle progression.“A loss of CD34 expression occurred during cell culture; this loss was enhanced by vitamin D3 , but prevented partly by bryostatin 5.”
“ Bryostatin 5 induced a significant (p = 0.00006) increment in esterase activity in a majority of the samples, which was further enhanced by vitamin D3.”
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