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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Vitamin D and Anti-Asthmatic Agents

Research Papers that Mention the Interaction

VD reduced infiltrated inflammatory … airway resistance of asthmatic mice , decreased serum levels of interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, increased serum levels of IL-10, … Bcl-2-associated X and caspase-3 expression, downregulated HMGB1 and TLR4, NF-κB and phosphorylated-NF-κB p65 expression.
VD was able reduce the inflammatory response of asthmatic mice and apoptosis in lung tissue through the HMGB1/TLR4/NF-κB signaling pathway.
Molecular medicine reports  •  2018  |  View Paper
Furthermore, treatment with vitamin D3 enhanced activation of the Nrf2/HO-1 pathway in the airways of asthmatic mice.
Molecular medicine reports  •  2016  |  View Paper
We assessed the mechanisms by which Vit D modulates the enhancing effects of proinflammatory cytokines tumor necrosis factor-α (TNF-α) and IL-13 on intracellular Ca(2+) ([Ca(2+)]i) levels and remodeling in nonasthmatic versus asthmatic human ASM.
Annals of the American Thoracic Society  •  2016  |  View Paper
Results Univariate analysis of the relationship between asthma and vitamin D showed that decreased vitamin D levels were associated with significantly increased odds of asthmatic state (P=0.002).
Allergy, asthma & immunology research  •  2011  |  View Paper