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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“ Rabbit skeletal muscle glycogen synthase was inhibited by pyridoxal 5'-phosphate and irreversibly inactivated after sodium borohydride reduction of the enzyme-pyridoxal-P complex.”
Catalytic site of rabbit glycogen synthase isozymes. Identification of an active site lysine close to the amino terminus of the subunit.“ Pyridoxine stimulated the generation of prostaglandin E2 in rabbit kidney medulla slices.”
“ Pyridoxal phosphate reacts with not only the lysyl residue(s) essential for enzymatic activity but also other reactive lysyl residues in rabbit muscle lactate dehydrogenase (EC 1.1.1.27).”
“Abstract Glycerol-3-phosphate dehydrogenase (EC 1.1.1.8) from rabbit skeletal muscle is inhibited by pyridoxal-5′-phosphate.”
“Pyridoxal 5'-phosphate PLP ) in aqueous solutions can form a Schiff base complex with 14 and 16 lysine residues of rabbit and sturgeon muscle aldolases (EC 4.1.2.13), respectively.”
“The results suggest that certain enzymes, including rabbit muscle and spinach aldolases, but not rabbit liver aldolase, contain a specific site which interacts with pyridoxal phosphate , and that the conformation of this site changes in the pH range between 8.0 and 8.5”
“ Abstract Pyridoxal phosphate , a reversible inhibitor of rabbit muscle aldolase, is found also to act as a photosensitizing agent for specific histidine residues of this enzyme, as well as of spinach leaf aldolase.”
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