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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Vitamin B 12
supplement:
Vitamin C
Research Papers that Mention the Interaction
“Accordingly, in the study of Ciccarelli et al.5, the antiparasitic effect of Bnz treatment was further enhanced by the coadministration of cyanocobalamin and ascorbic acid.”
“Moreover, ascorbate peroxidase activity is significantly increased by cyanocobalamin, and ascorbic acid is known to intensify the antiparasitic activity of cyanocobalamin.”
“Often they are administered simultaneously; chemically they are incompatible, as ascorbic acid (redox compound) inactivates cyanocobalamin.”
“The combination of ascorbic acid and cyanocobalamin is the problem of pharmacy.”
“Of major concern has been the influence of ingesting gram amounts of ascorbic acid on renal calcium oxalate stones, systemic conditioning, uricosuria, vitamin B12 destruction, mutagenicity, and iron overload.”
“Of major concern has been the influence of ingesting gram amounts of ascorbic acid on renal calcium oxalate stones, systemic conditioning, uricosuria, vitamin B12 destruction, mutagenicity, and iron overload.”
“The absorption of cyanocobalamin , the most stable analogue but not found in quantity in the diet, is slightly increased by ascorbic acid.”
The Effect of Megadose Ascorbic Acid Ingestion on the Absorption and Retention of Vitamin B12 in Man“Having noted the effect of ascorbic acid in vitro we considered the possibility of an effect in vivo and now have evidence that very high oral doses of ascorbic acid can produce a lowering of vitamin B12 activity as measured by this technique.”
“In recent research with cobalt-ascorbate plus vitamin C, we demonstrated that when B-12 is combined with vitamin C , the cobalt nucleus of B-12 attaches to a carbon on vitamin C, forming cobalt ascorbate.”
Effect of combined ascorbic acid and B-12 on survival of mice with implanted Ehrlich carcinoma and L1210 leukemia.“Feeding on ascorbic acid contributed to a higher content of the vitamin B12 in comminuted meat and in the egg yolk, this bearing evidence to the existance of an interrelation between the vitamins B12 and C.”
“The correlation analysis revealed that 25-hydroxyvitamin D3 (r=0.792, P<0.01), vitamin B12 (r=0.635, P<0.01) and vitamin C (r=0.703, P<0.01) were negatively correlated with serum NO level.”
Correlation analysis between 25-hydroxyvitamin D3, vitamin B12 and vitamin C and endothelial function of patients with CHD“ CC undergoes photolysis in acidic and alkaline media to form HC and the reaction is enhanced in the presence of AA.”
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