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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Vitamin B 12
drug:
Lamotrigine
Research Papers that Mention the Interaction
“In addition, Vitamin B12 and its combination with LTG decreased levels of total oxidative status (TOS), oxidative stress index (OSI), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and increased total antioxidant status (TAS) levels in the hippocampus and cerebral cortex.”
“In the present study, we aimed to test the hypothesis that vitamin B12 and their combination with lamotrigine prevents behavioral deficits, hippocampal damage, oxidation, and proinflammatory state during epileptogenesis.”
“ Vitamin B12 and its combination with LTG suppressed epileptogenesis and improved the performance of rats in the passive avoidance test.”
Protective effects of lamotrigine and vitamin B12 on pentylenetetrazole-induced epileptogenesis in rats
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