supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Vitamin B 12
drug:
Gentamicin
Research Papers that Mention the Interaction
“Also, cobalamin significantly improved serum electrolytes (sodium and potassium) levels which were disturbed by gentamicin.”
“ Cobalamin significantly compensated deficits in the antioxidant defense mechanisms, suppressed lipid per oxidation and ameliorated renal tissue damage mediated by gentamicin.”
“Results Cobalamin significantly increased creatinine clearance levels and renal blood flow which were reduced by gentamicin.”
Effects of Cobalamin (Vitamin B12) on Gentamicin Induced Nephrotoxicity in Rat.“violaces 1935 in the synthetic medium the level of gentamicin biosynthesis increased on the average by 2--2.5 times when cyancobalamine , methylcobalamine, L-methionine or L-serine were added to the medium.”
[Role of the components in the methylation system in the cobalamin-dependent gentamycin biosynthesis by a Micromonospora purpurea culture].“It was shown that … cobalt ions or vitamin B12 to the fermentation medium resulted … increase in the level of gentamicin accumulation, the relative content of the most methylated components C1 and C2 in the gentamicin … being increased, while the content of the least methylated components CIa and "minors" decreased.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback