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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Vitamin B 12 and Adenosylcobalamin

supplement:

Vitamin B 12

drug:

Adenosylcobalamin

Research Papers that Mention the Interaction

“In the presence of ATP and Mn2+, enzyme-bound hydroxocobalamin, cyanocobalamin and methylcobalamin were rapidly displaced by added adenosylcobalamin.”
The mechanism of in sutu reactivation of glycerol-inactivated coenzyme B12-dependent enzymes, glycerol dehydratase and diol dehydratase.
Journal of nutritional science and vitaminology  •  1982  |  View Paper
“Pyridoxal- P -modified enzyme was no longer able to bind cyanocobalamin (a competitive inhibitor of adenosylcobalamin).”
Chemical modification of coenzyme B12-dependent diol dehydrase with pyridoxal 5'-phosphate: lysyl residue essential for interaction between two components of the enzyme.
Archives of biochemistry and biophysics  •  1981  |  View Paper
“ Cyanocobalamin , a potent competitive inhibitor of adenosylcobalamin , protected the essential residue, but not the nonessential one, against the modification by these reagents.”
Reactive sulfhydryl groups of coenzyme B12-dependent diol dehydrase: differential modification of essential and nonessential ones.
Archives of biochemistry and biophysics  •  1981  |  View Paper