Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Vitamin A and Vitamin C

supplement:

Vitamin A

supplement:

Vitamin C

Research Papers that Mention the Interaction

Adding vitamin A or E counteracts the effect of ascorbic acid in inhibiting PMP22 expression.
Muscle & nerve  •  2008  |  View Paper
vitamin A …], vitamin C intake with IL-1β [R = -0.25], zinc intake with PGE2 [R = -0.30], IL-2 [R = -0.23], and the activity of …], IL-1β [R = -0.23] and IL-2 [R = -0.25], and selenium intake with PGE2 [R = -0.21] (P < 0.05).
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition  •  2019  |  View Paper
Conclusions: We demonstrate for the first time the synergistic interference of ascorbic acid and retinol on the measurement of uric acid in plasma.
Results: Among the different combinations of vitamins tested, only retinol potentiated the antioxidant effect of ascorbic acid.
We established that ascorbic acid interference is potentiated by regeneration of reduced ascorbic acid by retinol.
Clinical chemistry and laboratory medicine  •  2010  |  View Paper
Vitamin C and methionine have been found to reduce the toxicity of arsenicosis'l-', Retinoids or vitamin A is associated with clinical regression of the disease, but vitamin E has been found to potentiate the protective effect of vitamin A against the toxicity.
Tropical doctor  •  2003  |  View Paper
A combination of vitamins C and E (ascorbic acid, tocopherol) or solitary supplementation with vitamin A (retinoic acid) prevented lipid-peroxidation.
Cell and Tissue Research  •  2004  |  View Paper
A further increase in vitamin A intubation had an adverse effect on ascorbic acid concentrations in the plasma and brain.
Moderate amounts of vitamin A intubation increased ascorbic acid concentration in the liver, kidney, brain and plasma.
British poultry science  •  2000  |  View Paper
Further study revealed that ascorbic acid reduced MTT to formazan, which was profoundly increased by a very small amount of retinol , whereas retinol alone had no effect.
Journal of cellular biochemistry  •  2000  |  View Paper
Vitamin A decreased DNA adduct levels by 70% and Vitamin C by 90% in kidney.
Cancer letters  •  1997  |  View Paper
A hitherto unknown synergism exerted by retinol (vitamin A) and L-ascorbic acid (vitamin C) was discovered using endothelial cells.
Biochemical and biophysical research communications  •  1985  |  View Paper
…)ascorbic acid … vitamin A ; (b) ascorbic acid in the diet prevented or blocked the decrease in liver ascorbic acid in vitamin A deficiency but not at the …, and (d) ascorbic acid had no inhibitory effect on cholesterol synthesis and no interaction between retinyl acetate and ascorbic acid was observed.
The Journal of nutrition  •  1980  |  View Paper
Show More