Possible Interaction: Vitamin A and Retinyl Palmitate

“In addition, when vitamin A was given with the noon meal, the ensuing concentrations of retinyl palmitate were also higher after ingestion of the 60%-carbohydrate diet.”

“The retinol supplementation caused a significant increase in the plasma concentrations of retinol, retinyl palmitate , lutein and alpha-tocopherol, especially retinyl palmitate as well as the skin concentrations of retinol and retinyl palmitate.(ABSTRACT TRUNCATED AT 250 WORDS)”

“On average, for every 10,000 IU of retinyl palmitate per day, the serum retinol concentration increased by 13 micrograms/l after 3 months (an increase of 2%) and 12 micrograms/l after 6 months of supplementation (2% increase).”

“In addition, pre-administration of RP increased serum retinol concentrations and suppressed tumor growth.”

“The growth of tumors was inhibited with increasing serum retinol concentrations obtained post-administration of RP.”

“These results indicate that administration of RP can maintain retinol concentrations in the body and that this might suppress cancer cell growth and attachment.”

“These data suggest that retinyl palmitate supplementation can modulate the impaired balance of Th1 and Th2 cells and vitamin A products that may be involved in the therapeutic mechanism of vitamin A in MS patients.”

“A single oral supplementation with 20,000 IU vitamin A caused a two- to three-fold increase of retinol and retinyl palmitate in the LDL isolated 8 h after the supplementation.”

“2 Plasma concentrations of retinyl palmitate were higher after 50 mg retinol given as an oral supplement compared with 50 mg as liver; there was no significant difference between the 150 mg doses.”

“Blood levels of both compounds increase upon oral ingestion of all-trans-retinyl palmitate , to a greater extent with higher amounts of ingested retinyl palmitate.”

“Supplementation with higher doses of vitamin A over the study period significantly increased liver retinol and retinyl palmitate concentrations in adult mice.”

“ Vitamin A supplementation with BC or RE in early life differentially affects WAT and may thus entail different outcomes regarding adiposity programming.”