Possible Interaction: Vitamin A and Palmitate

“A synergistic effect of vitamin A palmitate on the phototoxicity of combinations containing avobenzone was observed.”

“ Vitamin A palmitate significantly increased the GC density after treatment.”

“In the LX‐2 human immortalized HSCs, with scant lipid droplets and features of activated HSCs, we found that the upregulation of ADRP mRNA by palmitate is potentiated by retinol , accompanied by increased ADRP protein, generation of retinyl palmitate, and lipid droplet formation.”

“A direct dose-response effect was observed, in that the more retinol palmitate was injected, the more CL was observed.”

“A marked reduction in the concentration of plasma proteins occurred in rats treated with CaEDTA and vitamin A palmitate.”

“The importance of this enzymic step in … absorption of an oral dose of vitamin A palmitate is shown by the finding that protein malnutrition reduced only slightly the final liver stores when vitamin A in its different forms (palmitate, acetate or alcohol) was injected directly into the blood stream.”

“The vitamin A alcohol content of the intestine, plasma and liver of chicks dosed with vitamin A palmitate was decreased by protein restriction.”

“Our results suggest that retinol palmitate pretreatment has a protective effect against myocardial I/R injury by maintaining the balance between intracellular oxidants and antioxidants.”