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“ Serum retinol concentrations correlated inversely with IL-10 and TGF-β productions in CD4+CD25highFoxp3+ T cells isolated from children with VL stimulated with leishmanial antigens.”
“Mitogen-stimulated IL-2, IL-4 and TNFalpha increased significantly (P < 0.05) in the vitamin A but not placebo group after supplementation, while IL-10 production was significantly and negatively correlated with vitamin A stores (P < 0.05).”
The British journal of nutrition • 2009 | View Paper
“ Vitamin A caused inhibition of IL-10 secretion by cells from adults, but it did not significantly affect this function in cells from newborns except when high unphysiological doses were applied.”
“Furthermore, vitamin A supplementation was significantly associated with an increased ratio of mitogen‐induced proinflammatory cytokine (IFN‐γ) to anti‐inflammatory cytokine ( IL‐10 ) during pregnancy and in the postpartum period.”
Clinical and experimental immunology • 2006 | View Paper
“Furthermore, VA supplementation decreased anti-inflammatory interleukin-10 and heat shock protein 70 expression, important factors for positive exercise adaptations and tissue damage prevention.”