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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“We find that both ascorbate and RA or retinol promote the derivation of induced pluripotent stem cells synergistically and enhance the erasure of epigenetic memory.”
“We found that retinol/retinoic acid vitamin A ) and ascorbate (vitamin C) synergistically diminish DNA methylation levels and in doing so enhance the generation of naïve pluripotent stem cells.”
Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms“It was hypothesized that the extra intake of the antioxidants would spare vitamin C … as shown previously after supplementation with vitamin C. A significant increase in plasma ascorbate concentration was observed after β-carotene supplementation, but not … A. Extra intake of either β-carotene or vitamin A slightly, … concentrations.”
Copper status in rats fed diets supplemented with either vitamin E, vitamin A, or β-carotene“Both the MDA formation and the loss of latency in either the Fe3+-ADP + ascorbate or the Fe2+ system were effectively prevented by the presence of vitamin A or vitamin E.”
“IT was initially suggested that vitamin A-deficiency leads to an interference in the biosynthesis of ascorbic acid, because depletion of vitamin A was found to cause a fall in the tissue-levels of ascorbate and diminished urinary ascorbic acid excretion in animals1–3.”
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