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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Viomycin
supplement:
Polypeptides
Research Papers that Mention the Interaction
“ Viomycin inhibited polypeptide synthesis and translocation of peptidyl-tRNA on ribosomes derived from a sensitive strain of M. smegmatis (R-15), but not significantly on ribosomes from viomycin-resistant mutants (R-31 and R-43).”
Viomycin resistance: alterations of either ribosomal subunit affect the binding of the antibiotic to the pair subunit and the entire ribosome becomes resistant to the drug.“The basic peptide antibiotic viomycin rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis.”
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