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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Vincristine
supplement:
Vitamin C
Research Papers that Mention the Interaction
“ Ascorbic acid , a ROS scavenger, inhibited ROS generation as well as caspase-9 and -3 activation and cell death induced by VCR.”
Vincristine induced apoptosis in acute lymphoblastic leukaemia cells: a mitochondrial controlled pathway regulated by reactive oxygen species?“Co-treatment or 96 h pre-treatment with ascorbic acid resulted in potentiation of the vincristine effect on the resistant, but not on the sensitive, cell line.”
“Interestingly, the VCR resistance of the PC-9/VCR cell line was partially reversed by ascorbic acid , and the drug uptake was enhanced.”
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