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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Vinblastine
supplement:
Kaempferol
Research Papers that Mention the Interaction
“This study demonstrates that some …, i.e., flavonols (quercetin and kaempferol ) and isoflavones (genistein and daidzein) markedly increase the sensitivity of the … human cervical carcinoma KB-V1 cells (high Pgp expression) to vinblastine and paclitaxel dose-dependently, and also decrease the … of these anticancer- drugs in KB-V1 cells.”
Inhibition of P-Glycoprotein Function and Expression by Kaempferol and Quercetin“Biochanin-A, genistein, quercetin, chalcone, silymarin, phloretin, morin, and kaempferol , at 100 microM concentrations, all significantly increased the accumulation of both DNM and VBL in Panc-1 cells, with morin increasing DNM and VBL accumulation by 546 +/- 50% (mean +/- SE, n = 9) and 553 +/- 37% (n = 9), respectively.”
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