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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Vigabatrin
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“No significant differences in terms of efficacy have been documented, though a combination of ACTH and vigabatrin seems to be associated with better long-term outcomes.”
Treatment of infantile spasms: why do we know so little?“ Vigabatrin in combination with either Adrenocorticotropic hormone (ACTH) or Prednisolone showed better seizure control in comparison to monotherapy and other combination modalities.”
“Given that vigabatrin has a gabaergic action and increased levels of ACTH , may explain this relationship but this must be confirmed with the best knowledge of the intimate mechanisms of these serious epileptic encephalopathies.”
“Moreover, there was a significant attenuation of CCK-induced elevation of ACTH and cortisol levels following vigabatrin treatment.”
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